In addition, the hydroxylase enzyme 25-hydroxycholecalciferol-1-hydroxylase, which is answerable for manufacturing of essentially the most lively, hormonal type of vitamin D, calcitriol, requires magnesium as its cofactor. Boron significantly improves magnesium absorption and deposition in bone, one more useful effect of boron’s inhibition of 17β-estradiol degradation. Magnesium’s importance, in bone alone, is illustrative of the widespread ramifications of boron insufficiency. Therefore, boron’s helpful hormonal effects are prone to be a results of its basic impact on vicinal hydroxylations of steroids. Stanhope KL. Consuming fructose-sweetened, not glucose-sweetened, drinks increases visceral adiposity and lipids and reduces insulin sensitivity in overweight/obese people.