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If indicators or symptoms suggest a severe cutaneous antagonistic reaction, use of this drug should not be resumed and various therapy should be considered. If a rash happens, the patient must be evaluated for signs and symptoms of SCARs. Abrupt withdrawal of phenytoin in epileptic sufferers may precipitate status epilepticus. When, within the judgment of the clinician, the need for dosage discount, discontinuation, or substitution of other anticonvulsant medication arises, this ought to be accomplished progressively. However, in the event of an allergic or hypersensitivity response, more fast substitution of different therapy could additionally be essential.